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Sigma
Angiotensin I human acetate salt hydrate
A9650 -
≥90% (HPLC)
DOWNLOAD MSDS (PDF)Synonym: Hypertensin I
CAS Number: 70937-97-2
Empirical Formula (Hill Notation): C62H89N17O14 · xC2H4O2 · yH2O
Molecular Weight: 1296.48 (anhydrous free base basis)
MDL number: MFCD00133091
PubChem Substance ID: 24891483
Properties
| Related Categories | Angiotensins, Application Index, Cell Signaling Enzymes, Chymase and Related Products, Neuropeptides, |
| assay | ≥90% (HPLC) |
| mol wt | mol wt 1296 Da by calculation (Average Mass) |
| storage temp. | −20°C |
| Gene Information | Research your gene in Your Favorite Gene powered by Ingenuity human ... AGT(183) |
Description
Amino Acid Sequence
Asp-Arg-Val-Tyr-Ile-His-P
Antibody Adsorbant
Asp-Arg-Val-Tyr-Ile-His-P
Biochem/physiol Actions
Angiotensin I is a putative neurotransmitter. It is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.
Price and Availability
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Documents
Certificate of Analysis
Certificate of Origin
| A9650 - Product Information Sheet (55 KB) |
| Neuropeptidases (252 KB) |
| Neuropeptidases Classification (197 KB ) |
| Gene Information |
| Structure Search |  |
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Safety Information
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
Technical information & documentation associated with this product is available in the Safety & Documentation tab.
Articles
Plasma Derived Proteins and Enzymes
Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Gas chromatography
References
Baker, E.S., et al., Simultaneous fragmentation of multiple ions using IMS drift time dependent collision energies. J. Am. Soc. Mass Spectrom. 19, 411-9, (2008) Abstract
Burkitt, W.I., et al., Toward Système International d'Unité-traceable protein quantification: from amino acids to proteins. Anal. Biochem. 376, 242-51, (2008) Abstract
Costerousse, O., et al., Angiotensin I-converting enzyme (kininase II) in cardiovascular and renal regulations and diseases. Biol. Res. 31, 161-167, (1998)
Ferrario, C.M., et al., Novel angiotensin peptides regulate blood pressure, endothelial function, and natriuresis. J. Am. Soc. Nephrol. 9, 1716-1722, (1998)
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